Recently, a lymphatic endothelial cell origin of cancer types, namely the true sense of lymphatic sarcoma, the Fourth Military Medical University, was first discovered and confirmed. The discovery, to fill the WHO classification of tumors in the lymphatic lymphatic malignancies vacant space, the classification of oncology, diagnosis and treatment of important theoretical and clinical significance.
It is understood that the tumor from the Fourth Military Medical University, Department of Pathology and Pathophysiology, Wang Zhe, Huang Professor Gao Liangwei led the research team found, and Name it The paper written, has full authority published in the International Journal of Oncology Clinical Oncology (
According to reports, the tumor often occurs in young patients with bone and soft tissue pain in patients with clinical manifestations of tumor growth, tumor locally redness, swelling, heat, pain such as purulent inflammation, accompanied by body heat, elevated white blood purulent inflammation.
tumor shape is very special, abundant cytoplasm by a single epithelioid cells, eosinophilic cytoplasm, membrane clear; bubble-like tumor cell nucleus large, round or oval round, open chromatin, with huge eosinophilic nucleolus; tumors seen a lot of neutrophil infiltration, and there are many micro-abscess formation. The tumor grew rapidly, early local recurrence and lymph node metastasis, no response to multiple chemotherapy regimens, patients after 4 months in the pathogenesis of widespread metastasis and died of severe complications. Can puncture pus out of local tumor, but a variety of microbial cultures were negative result, a variety of antibiotics ineffective. By immunohistochemistry and electron microscopy techniques, failed to find the tumor cell specific differentiation.
Zhe, said inflammatory monomorphic undifferentiated sarcoma of the clinical manifestations, pathology and prognosis features unique, and has been found that the tumor is not the same as in the world WHO classification of tumors is not similar to the type of pathology. Royal College of Pathologists of Australia's official magazine of the new pathological type of tumor found was reported.
tumor type is the first time by the Fourth Military Medical University, discovered and named, with independent intellectual property rights, is the pathology community of scholars independently discovered and named the first new type of tumor .
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